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The Aurel Stodola Lecture Series commemorate the personality and seminal contributions of Prof. Aurel Stodola in the early 20th century whose work on applied thermodynamics has guided many engineers and engineering developments worldwide. The Department of Mechanical and Process Engineering (D-MAVT) elected Prof. Mark Davis as its speaker of the 2012 Aurel Stodola Lecture Series: |
![]() Prof. Mark Davis |
Prof. Mark Davis - Laureate of the Aurel Stodola Medal 2012
Aurel Stodola Lecture May 3,2012 Fighting Cancer with Nanoparticle Medicines Papyrus writings from 1600-1500 BC describe cancer and attempts at its treatment. Today, centuries later, cancer remains a devastating disease. Given the long history of difficulties in developing cancer therapies, why is there excitement about nanoparticle medicine (nanomedicines) for fighting cancer? In this lecture, I will present the current understandings of why these engineered, nanosized medicines (that are highly multifunctional chemical systems) have the potential to provide “game changing” ways to treat cancer. The nanoscale matters. I will illustrate this point by demonstrating how physical insights at the nanoscale allow for the development of nanoparticles that can function as intended in animals and humans. The data from humans will be used to show how we have translated two independent nanoparticle cancer therapeutics from laboratory curiosities to experimental therapeutics in human clinical trials. |
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